Tuesday, March 25, 2008

Proxy server

In computer networks, a proxy server is a server (a computer system or an application program) which services the requests of its clients by forwarding requests to other servers. A client connects to the proxy server, requesting some service, such as a file, connection, web page, or other resource, available from a different server. The proxy server provides the resource by connecting to the specified server and requesting the service on behalf of the client. A proxy server may optionally alter the client's request or the server's response, and sometimes it may serve the request without contacting the specified server. In this case, it would 'cache' the first request to the remote server, so it could save the information for later, and make everything as fast as possible.

Tuesday, March 18, 2008

SQL (Structured Query Language)

SQL (Structured Query Language) (pronounced /ɛskjuːˈɛl/ officially, although the unofficial pronunciation /ˈsiːkwəl/ is often used (see below)) is a database computer language designed for the retrieval and management of data in relational database management systems (RDBMS), database schema creation and modification, and database object access control management.

SQL is a standard interactive and programming language for querying and modifying data and managing databases. Although SQL is both an ANSI and an ISO standard, many database products support SQL with proprietary extensions to the standard language.

Monday, March 10, 2008

Toxicity of Metabolites

Many substances regarded as poisons are toxic only indirectly. An example is "wood alcohol," or methanol, which is chemically converted to formaldehyde and formic acid in the liver. It is the formaldehyde and formic acid that cause the toxic effects of methanol exposure. Many drug molecules are made toxic in the liver, a good example being acetaminophen (paracetamol), especially in the presence of alcohol. The genetic variability of certain liver enzymes makes the toxicity of many compounds differ between one individual and the next. Because demands placed on one liver enzyme can induce activity in another, many molecules become toxic only in combination with others.

Wednesday, March 05, 2008

Human-powered transport

Human-powered transport is the transport of person(s) and/or goods using human muscle power. Like animal-powered transport, human-powered transport has existed since time immemorial in the form of walking, running and swimming. Modern technology has allowed machines to enhance human-power.

Although motorization has increased speed and load capacity, many forms of human-powered transport remain popular for reasons of lower cost, leisure, physical exercise and environmentalism. Human-powered transport is sometimes the only type available (especially in underdeveloped or inaccessible regions), and is considered an ideal form of sustainable transportation.